WWOX: A New Therapeutic Target In Type 2 Diabetes-Associated Neurodegeneration
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چکیده
منابع مشابه
High Density Lipoprotein: A Therapeutic Target in Type 2 Diabetes
High density lipoproteins (HDLs) have a number of properties that have the potential to inhibit the development of atherosclerosis and thus reduce the risk of having a cardiovascular event. These protective effects of HDLs may be reduced in patients with type 2 diabetes, a condition in which the concentration of HDL cholesterol is frequently low. In addition to their potential cardioprotective ...
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متن کاملTherapeutic approaches to target inflammation in type 2 diabetes.
BACKGROUND Chronic inflammation may participate in the pathogenesis of insulin resistance, type 2 diabetes, and cardiovascular disease and may be a common denominator that links obesity to these disease states. CONTENT Epidemiologic studies have linked inflammatory biomarkers to incident diabetes and cardiovascular disease risk. Cellular and animal studies have provided support to the idea th...
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Background: Type 2 diabetes (T2D) is a chronic metabolic disorder in which beta-cells are destroyed. The islet amyloid polypeptide (IAPP) produced by beta-cells has been reported to influence beta-cell destruction. Objective: To evaluate if IAPP can act as an autoantigen and therefore, to see if CD8 + T-cells specific for this protein might be present in T2D patients. Methods: Peripheral blood ...
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ژورنال
عنوان ژورنال: Metabolism
سال: 2021
ISSN: 0026-0495
DOI: 10.1016/j.metabol.2020.154616